drug interactions that cause low blood glucose hypoglycemia can occur with nonsteroidal anti-inflammatory drugs for example ibuprofen , sulfa drugs, warfarin coumadin , miconazole oravig , fluconazole diflucan , voriconazole vfend , beta-blockers for example, propranolol inderal, inderal la, innopran xl , androgens for example fluoxymesterone androxy , chloramphenicol, cimetidine tagamet hb , ranitidine zantac , clarithromycin biaxin , mao inhibitors for example, isocarboxazid marplan and phenelzine nardil , mifepristone mifeprex , probenecid, quinolone antibiotics, and selective serotonin reuptake inhibitors for example paroxetine paxil , fluoxetine prozac , and sertraline zoloft .
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blood levels and or toxicity of innopran may be increased by coadministration with substrates or inhibitors of cyp2d6, such as online amiodarone, cimetidine, delavudin, fluoxetine, paroxetine, quinidine, and ritonavir.
renal impairment the pharmacokinetics of propranolol after administration of innopran xl have not been evaluated in patients with renal impairment.
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